BiologicAE. developability.

The developability tool is designed to help assess the suitability of a protein as a therapeutic candidate. This tool, along with the MHC profiling available as part of the immunogenicity tool, covers two key areas of the protein's potential for successful development: risks associated with production and yield; and risks associated with immunogenicity.

While there are no truly comprehensive or accurate tools for the assessment of development risk, a combination of chemical or enzymatic post translational modification, structural stability, and potential for aggregation of sequence give a view of potential risks through future development.


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